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ULK2 is the second mammalian ortholog of yeast ATG1 with a similar purpose in autophagy as ULK1 (Lee and Tournier, 2011); consequently, we reasoned that inhibiting ULK2 could well be vital for an ULK1 inhibitor meant to block autophagy.Here we describe the identification and characterization of BI-0115, a selective modest molecule inhibitor of LOX-